Postdoctoral Scientist Positions – Systems Oncology Group
· Salary in the range of £31,604 – £41,929 per annum (depending on qualifications and experience)
· Duration of posts: Fixed term for 3 years
· Closing date: 20th May 2018
· These positions are part of an ERC consolidator award to understand the evolutionary constraints of the tumour microenvironment on pancreatic cancer progression.
· Key qualities should include independent thinking, ability to work in a team and good communication skills, all of which are needed to efficiently work in a multidisciplinary team.
Postdoctoral Scientist (Computational) - Job Reference: MI/18/25
About the role:
You will develop an independent research project to interrogate cellular interactions in the tumour microenvironment and help identify key regulatory events that drive clonal selection. Using computational analysis of available and newly generated data (proteomics, single cell analysis) you will develop a framework to associate changes in tumour and stromal departments and to develop experimental testable hypotheses. You will be experienced in computational biology/bioinformatics, analysis of quantitative signalling data and expression data.
You should have a PhD in systems biology, engineering, computational biology or a relevant field. Experience in computational modelling, data integration and analysis is essential to the success of the project.
Postdoctoral Scientist - Job Reference: MI/18/26
About the role:
You will develop an independent research project to address how tumour cell clonal diversity directs stromal interactions. This will include development of in vitro co-culture models of tumour and stromal cells, systematic analysis of exchanged signal cues and mapping of regulated signalling pathways by quantitative mass spectrometry and single cell Mass Cytometry. You will be experienced in protein biochemistry, analysis of cellular signalling, primary cell culture and FACS.
You should have a PhD in biochemistry or a relevant field. Experience in protein biochemistry, analysis of cell signalling in cell culture (using 2D and 3D models) and analysis of primary tumours is essential to the success of the project.
Postdoctoral Scientist - Job Reference: MI/18/27
About the role:
You will develop an independent research project to address how the tumour microenvironment selects specific tumour cell populations. This will include development and interrogation of in vivo pancreatic cancer models, in vitro co-culture models of tumour and stromal cells and analysis of signalling cues and regulated pathways. You will be experienced with in vivo cancer models, primary cell culture and FACS.
You should have a PhD in cell biology or a relevant field. Experience with in vivo cancer models, single cell analysis (FACS/CyTOF, multiplexed IF/IHC and expression analysis) and primary tumour analysis are essential to the success of the project.
How to apply?
To apply for these positions please visit their website: http://www.cruk.manchester.ac.uk/Opportunities/Opportunities-Home
Informal enquiries can be directed to Dr Claus Jorgensen via email: claus.jorgensen@ cruk.manchester.ac.uk.