Principal Bioinformatician

  • Starting salary from: £30,100-£49,100 per annum (dependent upon experience)
  • Job Ref: MI/18/15
  • Duration: Fixed term until 31 March 2019 (in the first instance)


About the role:

As part of the expansion of the CRUK Manchester Institute Drug Discovery Unit (, we are seeking an enthusiastic and proactive expert in Drug Discovery Bioinformatics, to help drive our programmes from early target identification through to candidate selection and clinical evaluation.  An expert in the use of complex biological datasets to influence decision making, you will play a significant role in the identification and prioritisation of new drug discovery targets.  You will also have significant influence in defining our biomarker strategy for patient stratification and for validating in vivo markers of therapeutic response.

Alongside these project roles, you will influence and develop our group capabilities and collaborations in bioinformatics and seek innovative ways of interacting with our project teams to maximise the use of complex biological datasets in the delivery of human drug candidates.  You will also provide support and direction for the on-going support and future enrichment of our Dotmatics informatics platform across all drug discovery disciplines.


About you:

You should have a PhD in Biochemistry, Molecular Biology, Biology or Bioinformatics (or related field) or a relevant postgraduate degree in these disciplines plus substantial relevant experience in analysing high-throughput genomics data sets.  In addition you will have significant demonstrable experience analysing biological datasets including next generation sequencing (NGS) and other genomic data. 


Why choose Cancer Research UK Manchester Institute?

The Cancer Research UK Manchester Institute (, an Institute of The University of Manchester (, is a world-leading centre for excellence in cancer research.  The Institute is core funded by Cancer Research UK (, the largest independent cancer research organisation in the world.  We are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside. 

We are partnered with The Christie NHS Foundation Trust (adjacent to the CRUK MI Paterson Building) in South Manchester (, one of the largest cancer treatment centres in Europe.  These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

How to apply?

To apply for this position please visit our website:

For any informal enquiries about these posts, please contact Dr Allan Jordan via email:

The deadline for receipt of applications is: 29 March 2018.

Start Date

28th February 2018

Closing Date

29th March 2018