- Salary in the range of £30,000 - £39,800 (dependent upon qualifications and experience)
- Job Ref: MI/17/15
- Duration: 3 years in first instance
A 3 year position is available in the laboratory of Georges Lacaud to investigate the role of the epigenetic factor MOZ in normal haematopoiesis and leukaemia. They, and others, have recently established that MOZ is exquisitely essential for the maintenance of haematopoietic stem cells (HSCs). They also identified transcriptional targets of the fusion protein MOZ-TIF2 that are specifically expressed in leukaemic cells and might represent potential therapeutic targets. The aims of this project are to investigate the molecular and cellular mechanisms underlying the critical role of MOZ in HSCs maintenance and to further validate and progress these potential therapeutic targets.
The successful applicant should have a PhD in molecular or cellular biology (or a relevant field). A background in haematopoiesis or leukaemia is desirable.
Informal enquiries should be directed to Georges Lacaud (email@example.com).
The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. They are adjacent to The Christie NHS Foundation Trust (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.
Their aim is to understand the fundamental basis of cancer and apply that knowledge to developing new treatment strategies for cancer patients. Our advanced research programmes span a spectrum of cancer research, from the molecular and cellular basis of cancer through to drug discovery, translational research and clinical trials.
The Institute has outstanding laboratory facilities and exceptional core services, including next generation sequencing, microarrays, confocal microscopy, bioinformatics, histology and mass-spectrometry.
They are situated in Manchester, England, a vibrant and dynamic city that is surrounded by beautiful countryside and has excellent transport links both nationally and internationally.
To apply for this position please visit their website: www.cruk.manchester.ac.uk
For applicants who are unable to download this information from their website, please contact HR department on 0161 446 3231, email: firstname.lastname@example.org to have this information sent by post.
Closing date: 30th March 2017