Working together to
promote the advance
of all aspects of
cancer research.

Scientific Officer 2 - Clinical and Experimental Pharmacology

  • Salary in the range of £19,600 - £22,700
  • Job Ref: MI/17/08
  • Duration: Fixed term until 31st March 2022

They are currently looking for a Scientific Officer, funded by the Manchester Biomedical Research Centre to join the Clinical and Experimental Pharmacology Group (CEP) led by Prof Caroline Dive to help build upon our successful development of liquid biopsies. The post holder will join an expanding nucleic acids biomarkers team who are establishing personalised medicine approaches using a range of molecular biology techniques applied to patient samples with an emphasis on blood samples. The primary objective of the post is to develop and apply biomarker assays targeting a panel of cancer related genes present in circulating tumour DNA (ctDNA) obtained from the blood of patients enrolled on the TARGET study in the Early Phase Trials Unit at the Christie Hospital.

The applicant will be part of a team responsible for ensuring the ctDNA results are compliant with Good Clinical Practice (GCP) to ensure the data can be used to inform cancer patient treatment decisions. In addition, there will also be the opportunity to play a role in the evaluation and technical development of novel biomarker assays in order to continually improve personalised medicine approaches.

The successful applicant should have a BSc in Biological Sciences or related subject (or equivalent relevant experience), plus relevant experience of working in a laboratory environment. Highly desirable is a keen interest in cancer biology, previous experience of molecular biology techniques, ideally working in a cancer research setting. Knowledge of GCP regulations although not essential would be beneficial.

This post is funded from 1st April 2017. For any informal enquiries about this post, please contact Dr Ged Brady e-mail

The Cancer Research UK Manchester Institute (, an Institute of The University of Manchester (, is a world-leading centre for excellence in cancer research.  The Institute is core funded by Cancer Research UK (, the largest independent cancer research organisation in the world.  They are adjacent to The Christie NHS Foundation Trust (, one of the largest cancer treatment centres in Europe.  These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

Their aim is to understand the fundamental basis of cancer and apply that knowledge to developing new treatment strategies for cancer patients.  Their advanced research programmes span a spectrum of cancer research, from the molecular and cellular basis of cancer through to drug discovery, translational research and clinical trials.

The Institute has outstanding laboratory facilities and exceptional core services, including next generation sequencing, microarrays, confocal microscopy, bioinformatics, histology and mass-spectrometry. 

They are situated in Manchester, England, a vibrant and dynamic city that is surrounded by beautiful countryside and has excellent transport links both nationally and internationally.

To apply for this position please visit their website:

The deadline for receipt of applications is: 23rd March 2017

Interviews will take place: 3rd April 2017

Start Date

21st February 2017

Closing Date

23rd March 2017