Precision Medicine and Cancer Models - Developing strategies to enhance clinical response
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21st November 2017
The Royal Society of Medicine, London, UK
The use of preclinical and clinical information to inform patient selection for novel cancer therapies is key, with the development and use of models to interrogate target dependencies based on molecular pathology being well-established. Recent studies also suggest that it may be valuable to integrate additional information into patient selection hypotheses, including considerations of tumor metabolism, the type and extent of immunological infiltrate in a tumour, or the acquisition of a mesenchymal phenotype. This one-day conference involves leading investigators working at the translational interface in oncology to better define disease subtypes and guide precision medicine decisions.
An interactive poster/poster discussion session will also be held relevant to anyone involved in modelling cancer disease and assessing therapeutic responses.
Use of models and clinical material to inform subtyping of colorectal cancer
Classifying tumours based on immunogenic subtype
Experimental strategies to reveal therapeutic targets in liver cancer
Modelling the microenvironment in ERa-positive breast cancer
Modelling pancreatic adenocarcinoma and potential therapeutic approaches
J P Medema (Academic Medical Centre, Netherlands)
Jerome Galon (Cordeliers Research Centre, Paris)
Nicholas Turner (The Institute of Cancer Research, London)
Lars Zender (University Hospital Tubingen, Germany)
Cathrin Brisken (ISREC - Swiss Instittute for Experimental Cancer Research, Switzerland)
Andrew Biankin (CRUK Beatson Instiute, Glasgow)